Presentation and management of ACE-I induced angioedema in the Emergency Department: an observational study
نویسندگان
چکیده
Background Angioedema of the upper airway is a life-threatening Emergency Department (ED) presentation with many etiologies. Angiotensin converting enzyme-inhibitor (ACE-I) use is one cause of non-mast cell mediated angioedema. As the use of this medication class increases with our aging population, it is important to characterize the presentation and management of ACE-I induced angioedema (AAE), a rare but potentially severe side effect of this commonly prescribed medication class. The objectives of this study were to describe the incidence and management of AAE in the ED and to identify any epinephrine-induced morbidity.
منابع مشابه
ACE-I Angioedema: Accurate Clinical Diagnosis May Prevent Epinephrine-Induced Harm
INTRODUCTION Upper airway angioedema is a life-threatening emergency department (ED) presentation with increasing incidence. Angiotensin-converting enzyme inhibitor induced angioedema (AAE) is a non-mast cell mediated etiology of angioedema. Accurate diagnosis by clinical examination can optimize patient management and reduce morbidity from inappropriate treatment with epinephrine. The aim of t...
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BACKGROUND Recent data are lacking about the number of patients with angiotensin-converting enzyme inhibitor (ACEI)-induced angioedema who present to the emergency department (ED). Current management of the condition and clinical outcomes also are not known. OBJECTIVE To describe the clinical epidemiology of ACEI-induced angioedema in patients who present to the ED. METHODS We performed a m...
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OBJECTIVES/HYPOTHESIS To develop and validate a clinical algorithm for management of patients with angiotensin-converting enzyme inhibitor-induced angioedema (AIIA). STUDY DESIGN Prospective cohort observational study. METHODS Over 1 year, 40 patients with AIIA were evaluated by otolaryngology, underwent laryngoscopy, and were followed until disease resolution. The need for airway intervent...
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